Statistical Thinking and Precision Performance Metrics

• Statistical thinking to judge data trustworthiness
• Understanding of ASTM definitions and uses for various statistical terms and concepts
• Understanding common cause variation versus special cause variation
• Explanation of precision performance metrics such as repeatability, reproducibility, and site precision
• Business applications of precision performance metrics

 

Statistical Control Charts and Work Processes

• Methodology and work processes for setting up and maintaining Statistical Control Charts
• Monitoring test method performance over time as per ASTM D6299
• Hands-on exercises using QC/PLUS
• Specialized techniques for handling QC material batch transition
• Dealing with non-normal data

 

Bias and Relative Bias

• Overview of absolute and relative bias
• Assessing and Monitoring bias between different laboratory test methods or a laboratory test method and an on-line process analyzer
• Assessing and Monitoring bias versus industry over time
• Bias fundamentals and statistical techniques and control charts

 

QC Control Plan and Data Trustworthiness

• QC control plan and site readiness checklist
• How data trustworthiness impacts business performance of the enterprise
• Group participation in quiz questions to test participants’ understanding of the concepts presented